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  1. Flexor tendon injuries most commonly occur following a penetrating injury to the hand or wrist. These are challenging injuries and the standard treatment is surgical repair under general or regional anaesthesia.

    Authors: Grant S. Nolan, Ailbhe L. Kiely, Tomas Madura and Alexia Karantana

    Citation: Systematic Reviews 2020 9:264

    Content type: Protocol

    Published on:

  3. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19) which has rapidly spread worldwide. Several human randomized clinical trials assessing potential vaccines...

    Authors: Steven Kwasi Korang, Sophie Juul, Emil Eik Nielsen, Joshua Feinberg, Faiza Siddiqui, Giok Ong, Sarah Klingenberg, Areti Angeliki Veroniki, Fanlong Bu, Lehana Thabane, Allan Randrup Thomsen, Janus C. Jakobsen and Christian Gluud

    Citation: Systematic Reviews 2020 9:262

    Content type: Protocol

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  4. Early identification of patients at risk for postoperative delirium is essential because adequate well-timed interventions could reduce the occurrence of delirium and the related detrimental outcomes.

    Authors: Tayler A. Buchan, Behnam Sadeghirad, Nayeli Schmutz, Nicolai Goettel, Farid Foroutan, Rachel Couban, Lawrence Mbuagbaw and Benjamin T. Dodsworth

    Citation: Systematic Reviews 2020 9:261

    Content type: Protocol

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  5. Integrated care is a people-centered health delivery approach that ensures the comprehensiveness, quality, and continuity of service across the settings and levels of health systems. The World Health Organizat...

    Authors: Md Zabir Hasan, Shalini Singh, Dinesh Arora, Nishant Jain and Shivam Gupta

    Citation: Systematic Reviews 2020 9:260

    Content type: Protocol

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  6. Physical activity (PA) is a complex multidimensional human behaviour. Currently, there is no standardised approach for measuring PA using wearable accelerometers in health research. The total volume of PA is a...

    Authors: Tripti Rastogi, Anne Backes, Susanne Schmitz, Guy Fagherazzi, Vincent van Hees and Laurent Malisoux

    Citation: Systematic Reviews 2020 9:259

    Content type: Protocol

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  7. Previous studies on the impact of corona virus disease 2019 (COVID-19) on the mental health of the patients has been limited by the lack of relevant data. With the rapid and sustained growth of the publication...

    Authors: Jiyuan Shi, Ya Gao, Liang Zhao, Yuanyuan Li, Meili Yan, Ming Ming Niu, Yamin Chen, Ziwei Song, Ruixing Zhang, Lili Zhang and Jinhui Tian

    Citation: Systematic Reviews 2020 9:258

    Content type: Protocol

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  8. There is a complicated and exploitative history of research with Indigenous peoples and accompanying calls to meaningfully and respectfully include Indigenous knowledge in healthcare. Storytelling approaches t...

    Authors: Kendra L. Rieger, Sarah Gazan, Marlyn Bennett, Mandy Buss, Anna M. Chudyk, Lillian Cook, Sherry Copenace, Cindy Garson, Thomas F. Hack, Bobbie Hornan, Tara Horrill, Mabel Horton, Sandra Howard, Janice Linton, Donna Martin, Kim McPherson…

    Citation: Systematic Reviews 2020 9:257

    Content type: Protocol

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  9. The COVID-19 pandemic has created a sense of urgency in the research community in their bid to contribute to the evidence required for healthcare policy decisions. With such urgency, researchers experience met...

    Authors: Linda Biesty, Pauline Meskell, Claire Glenton, Hannah Delaney, Mike Smalle, Andrew Booth, Xin Hui S. Chan, Declan Devane and Catherine Houghton

    Citation: Systematic Reviews 2020 9:256

    Content type: Methodology

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  10. There is limited evidence for the comparative effectiveness of analgesic medicines for adults with low back pain. This systematic review and network meta-analysis aims to determine the analgesic effect, safety...

    Authors: Michael A. Wewege, Matthew K. Bagg, Matthew D. Jones and James H. McAuley

    Citation: Systematic Reviews 2020 9:255

    Content type: Protocol

    Published on:

  11. Overviews of reviews (overviews) provide an invaluable resource for healthcare decision-making by combining large volumes of systematic review (SR) data into a single synthesis. The production of high-quality ...

    Authors: Michelle Gates, Allison Gates, Samantha Guitard, Michelle Pollock and Lisa Hartling

    Citation: Systematic Reviews 2020 9:254

    Content type: Research

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  12. Prostate cancer accounts for about 10% of cancers affecting and claiming the lives of men. Studies have reported that women are better than men in recognition of the early manifestations of various cancers. Be...

    Authors: Ebenezer Wiafe, Kofi Boamah Mensah, Adwoa Bemah Boamah Mensah, Varsha Bangalee and Frasia Oosthuizen

    Citation: Systematic Reviews 2020 9:253

    Content type: Protocol

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  14. Globally, a total of 13.6 million women have died due to maternal causes from 1990 to 2015. Majority of these deaths occurred in resource-limited countries. Among the causes of these deaths, obstructed and pro...

    Authors: Asteray Assmie Ayenew and Biruk Ferede Zewdu

    Citation: Systematic Reviews 2020 9:251

    Content type: Research

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  15. Sickle cell disease (SCD) is an inherited autosomal recessive disorder caused by the replacement of normal haemoglobin (HbA) by mutant Hb (sickle Hb, HbS). The sickle-shaped red blood cells lead to haemolysis ...

    Authors: Britta Runkel, Birgit Klüppelholz, Anne Rummer, Wiebke Sieben, Ulrike Lampert, Claudia Bollig, Martina Markes, Ulrike Paschen and Konstanze Angelescu

    Citation: Systematic Reviews 2020 9:250

    Content type: Research

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  16. Systematic reviews are increasingly prevalent in environmental health due to their ability to synthesize evidence while reducing bias. Different systematic review methods have been developed by the US National...

    Authors: Stephanie M. Eick, Dana E. Goin, Nicholas Chartres, Juleen Lam and Tracey J. Woodruff

    Citation: Systematic Reviews 2020 9:249

    Content type: Research

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  17. Micronutrient deficiency affects the health and development of vulnerable population such as children and pregnant women. Measures such as fortification of food and supplementation have been implemented to pre...

    Authors: Eti Rajwar, Shradha S. Parsekar, Bhumika Tumkur Venkatesh and Zinnia Sharma

    Citation: Systematic Reviews 2020 9:248

    Content type: Research

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  18. Moxibustion is a common intervention of Chinese medicine (CM). Systematic reviews (SRs) on moxibustion are increasing. Although the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) s...

    Authors: Xuan Zhang, Ran Tan, Wai Ching Lam, Chung Wah Cheng, Liang Yao, Xiao-Qin Wang, Si-Yao Li, Qi-Ying Aixinjueluo, Ke-Hu Yang, Hong-Cai Shang, Tai-Xiang Wu, Ai-Ping Lyu and Zhao-Xiang Bian

    Citation: Systematic Reviews 2020 9:247

    Content type: Research

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  19. Pathways are frequently used to improve care for cancer patients. However, there is little evidence about the effects of pathways used in oncological care. Therefore, we performed a systematic review and meta-...

    Authors: Jolanda C. van Hoeve, Robin W. M. Vernooij, Michelle Fiander, Peter Nieboer, Sabine Siesling and Thomas Rotter

    Citation: Systematic Reviews 2020 9:246

    Content type: Research

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  20. Methamphetamine use and harms are rising rapidly. Management of patients with methamphetamine use disorder (MUD) and problematic methamphetamine use (PMU) is challenging, with no clearly established best appro...

    Authors: C. Hamel, K. Corace, M. Hersi, D. Rice, M. Willows, P. Macpherson, B. Sproule, J. Flores-Aranda, G. Garber, L. Esmaeilisaraji, B. Skidmore, A. Porath, R. Ortiz Nunez and B. Hutton

    Citation: Systematic Reviews 2020 9:245

    Content type: Protocol

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  21. Internalising problems, such as depression and anxiety, are common and represent an important economical and societal burden. The effectiveness of parenting interventions in reducing the risk of internalising ...

    Authors: Ilaria Costantini, Elise Paul, Deborah M. Caldwell, José A. López-López and Rebecca M. Pearson

    Citation: Systematic Reviews 2020 9:244

    Content type: Protocol

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  22. The exponential growth of the biomedical literature necessitates investigating strategies to reduce systematic reviewer burden while maintaining the high standards of systematic review validity and comprehensi...

    Authors: Shivani M. Reddy, Sheila Patel, Meghan Weyrich, Joshua Fenton and Meera Viswanathan

    Citation: Systematic Reviews 2020 9:243

    Content type: Research

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  23. Occupational exposure to cytotoxic drugs is associated with various unfavorable health outcomes. This protocol reports a methodology for a systematic review and meta-analysis that aims to systematically review...

    Authors: Laila Al Alawi, Elpidoforos S. Soteriades, Marilia Silva Paulo, Linda Östlundh, Michal Grivna, Fatima Al Maskari and Rami H. Al-Rifai

    Citation: Systematic Reviews 2020 9:242

    Content type: Protocol

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  24. Given a persistent nursing shortage in Canada and a decline in new nurses entering the profession, new graduate nurses (NGNs) are being hired into positions historically reserved for more experienced staff. Cr...

    Authors: Brandi Vanderspank-Wright, Michelle Lalonde, Janet Squires, Ian D. Graham, Nikolaos Efstathiou, Robin Devey Burry, Emily Marcogliese, Becky Skidmore and Amanda Vandyk

    Citation: Systematic Reviews 2020 9:241

    Content type: Protocol

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  25. A systematic literature review of researchers and healthcare professionals’ attitudes towards the secondary use and sharing of health administrative and clinical trial data was conducted using electronic data ...

    Authors: Elizabeth Hutchings, Max Loomes, Phyllis Butow and Frances M. Boyle

    Citation: Systematic Reviews 2020 9:240

    Content type: Research

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  26. Violence against women and girls (VAWG) has been significantly increased by the rise of conflict and insecurity in the territories under controlling so-called Islamic State of Iraq and Syria (ISIS). This revie...

    Authors: Shadab Shahali, Shahrooz Shariati and Ali Montazeri

    Citation: Systematic Reviews 2020 9:239

    Content type: Protocol

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  27. Negative pressure wound therapy (NPWT) is a widely used method of wound treatment. We performed a systematic review of randomised controlled trials (RCTs) comparing the patient-relevant benefits and harms of N...

    Authors: Yvonne Zens, Michael Barth, Heiner C. Bucher, Katrin Dreck, Moritz Felsch, Wolfram Groß, Thomas Jaschinski, Heike Kölsch, Mandy Kromp, Inga Overesch, Stefan Sauerland and Sven Gregor

    Citation: Systematic Reviews 2020 9:238

    Content type: Research

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  28. Within our inquiry into the implementation of breastfeeding policy in Malawi, Care Groups have been mentioned as a means to improve maternal and child health and nutrition outcomes. The ‘Care Group model’ is a...

    Authors: Pieternella Pieterse, Anne Matthews, Aisling Walsh and Ellen Chirwa

    Citation: Systematic Reviews 2020 9:237

    Content type: Protocol

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  29. Surgical specialities use extensive amounts of antimicrobials, and misuse has been widely reported, making them a key target for antimicrobial stewardship initiatives. Interventions informed by, and tailored t...

    Authors: Hazel Parker, Julia Frost, Nicky Britten, Sophie Robinson and Karen Mattick

    Citation: Systematic Reviews 2020 9:236

    Content type: Protocol

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  30. We aimed to synthesise data on issues related to stakeholder perceptions of privacy, trust, and transparency in use of secondary data. A systematic literature review of healthcare consumer attitudes towards th...

    Authors: Elizabeth Hutchings, Max Loomes, Phyllis Butow and Frances M. Boyle

    Citation: Systematic Reviews 2020 9:235

    Content type: Research

    Published on:

  31. Cardiovascular disease (CVD) is the leading cause of death in women, responsible for approximately a third of all female deaths. Pregnancy complications are known to be associated with a greater risk of incide...

    Authors: Charlotte Muehlschlegel, Harry Kyriacou, Abdulrahman Al-Mohammad, Lowri A. Foster-Davies, Fiona Simmons-Jones and Clare Oliver-Williams

    Citation: Systematic Reviews 2020 9:234

    Content type: Protocol

    Published on:

  32. Mental health (MH) problems are among the most important causes of morbidity and mortality for children and youth. Problems of lack of equity in child and youth MH services (CYMHS)—including, but not limited t...

    Authors: William Gardner, Stuart G. Nicholls, Graham J. Reid, Brian Hutton, Candyce Hamel, Lindsey Sikora, Mina Salamatmanesh, Laura Duncan, Katholiki Georgiades and Jason Gilliland

    Citation: Systematic Reviews 2020 9:233

    Content type: Protocol

    Published on:

  33. Lumbar spinal stenosis (LSS) and knee and hip osteoarthritis (OA) are prevalent conditions in the aging population and published literature suggests they share many symptoms and often are present at the same t...

    Authors: James J. Young, Jan Hartvigsen, Rikke K. Jensen, Ewa M. Roos, Carlo Ammendolia and Carsten Bogh Juhl

    Citation: Systematic Reviews 2020 9:232

    Content type: Protocol

    Published on:

  34. Dextro-transposition of the great arteries (d-TGA) is the most frequent cyanotic congenital heart pathology in neonates. Surgical correction of this condition is possible using the arterial switch operation (ASO)...

    Authors: Frederick Morfaw, Alvin Leenus, Lawrence Mbuagbaw, Laura N. Anderson, Rejane Dillenburg and Lehana Thabane

    Citation: Systematic Reviews 2020 9:231

    Content type: Research

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  36. International guidelines recommend education, exercise, and dietary weight management as core treatments to manage osteoarthritis (OA) regardless of disease severity or co-morbidity. Evidence supports the clin...

    Authors: Darren R. Mazzei, Ayoola Ademola, J. Haxby Abbott, Tolulpe Sajobi, Kevin Hildebrand and Deborah A. Marshall

    Citation: Systematic Reviews 2020 9:229

    Content type: Protocol

    Published on:

  37. Programs that integrate tuberculosis (TB) and human immunodeficiency virus (HIV) treatment aim to provide efficient treatment services and maximize successful treatment outcomes through the delivery of both TB...

    Authors: Benjamin Momo Kadia, Desmond Aroke, Kevin Pene Njefi, Joel Noutakdie Tochie, Frank-Leonel Tianyi, Reine Suzanne Kadia and Christian Akem Dimala

    Citation: Systematic Reviews 2020 9:228

    Content type: Protocol

    Published on:

  38. Patient prioritization is a strategy used to manage access to healthcare services. Patient prioritization tools (PPT) contribute to supporting the prioritization decision process, and to its transparency and f...

    Authors: Julien Déry, Angel Ruiz, François Routhier, Valérie Bélanger, André Côté, Daoud Ait-Kadi, Marie-Pierre Gagnon, Simon Deslauriers, Ana Tereza Lopes Pecora, Eduardo Redondo, Anne-Sophie Allaire and Marie-Eve Lamontagne

    Citation: Systematic Reviews 2020 9:227

    Content type: Research

    Published on:

  39. Several systematic reviews have reviewed the evidence relating to nature on aspects of children and adolescent’s health and wellbeing; however, none have looked at the associations or effectiveness of attendin...

    Authors: Avril Johnstone, Paul McCrorie, Rita Cordovil, Ingunn Fjørtoft, Susanna Iivonen, Boris Jidovtseff, Frederico Lopes, John J. Reilly, Hilary Thomson, Valerie Wells and Anne Martin

    Citation: Systematic Reviews 2020 9:226

    Content type: Protocol

    Published on:

  40. Osteosynthesis is the internal fixation of fractures or osteotomy by mechanical devices (also called hardware). After bone healing, there are two options: one is to remove the hardware, the other is to leave i...

    Authors: Barbara Prediger, Tim Mathes, Christian Probst and Dawid Pieper

    Citation: Systematic Reviews 2020 9:225

    Content type: Research

    Published on:

  41. Retention of participants is essential to ensure the statistical power and internal validity of clinical trials. Poor participant retention reduces power and can bias the estimates of intervention effect. Ther...

    Authors: Adel Elfeky, Katie Gillies, Heidi Gardner, Cynthia Fraser, Timothy Ishaku and Shaun Treweek

    Citation: Systematic Reviews 2020 9:224

    Content type: Research

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  42. Racism is increasingly recognised internationally as a key factor contributing to health disparities. A comprehensive body of strong research from international authors has reported negative associations betwe...

    Authors: Camila A. Kairuz, Lisa M. Casanelia, Keziah Bennett-Brook, Julieann Coombes and Uday Narayan Yadav

    Citation: Systematic Reviews 2020 9:223

    Content type: Protocol

    Published on:

  43. Atopic dermatitis (AD) is an inflammatory chronic condition that affects the skin of children and adults and has an important impact on the quality of life. Treatments for AD are based on environmental control...

    Authors: Luis Guillermo Gómez-Escobar, Hansel Mora-Ochoa, Andrea Vargas Villanueva, Loukia Spineli, Gloria Sanclemente, Rachel Couban, Elizabeth García, Edgardo Chapman and Juan José Yepes-Nuñez

    Citation: Systematic Reviews 2020 9:222

    Content type: Protocol

    Published on:

  44. With the dynamic advancement of digitalization, working environments are changing and risk for employee stress may be increasing. Work stress has been associated with a dysregulation of inflammatory processes ...

    Authors: Helena C. Kaltenegger, Linda Becker, Nicolas Rohleder, Dennis Nowak and Matthias Weigl

    Citation: Systematic Reviews 2020 9:221

    Content type: Protocol

    Published on:

  45. Expenditure on driver-related behavioral interventions and road use policy is often justified by their impact on the frequency of fatal and serious injury crashes. Given the rarity of fatal and serious injury ...

    Authors: Reneta Slikboer, Samuel D. Muir, S. S. M. Silva and Denny Meyer

    Citation: Systematic Reviews 2020 9:220

    Content type: Research

    Published on:

  46. Careers in healthcare involve an extensive interview process as transitions are made from one level of training to the next. For physicians, interviews mark the gateway from entrance into medical school, accep...

    Authors: Rajajee Selvam, Richard Hu, Reilly Musselman, Isabelle Raiche and Husein Moloo

    Citation: Systematic Reviews 2020 9:219

    Content type: Protocol

    Published on:

  47. The objective of this review was to examine the current guidelines for infection prevention and control (IPAC) of coronavirus disease-19 (COVID-19) or other coronaviruses in adults 60 years or older living in ...

    Authors: Patricia Rios, Amruta Radhakrishnan, Chantal Williams, Naveeta Ramkissoon, Ba’ Pham, Gordon V. Cormack, Maura R. Grossman, Matthew P. Muller, Sharon E. Straus and Andrea C. Tricco

    Citation: Systematic Reviews 2020 9:218

    Content type: Research

    Published on:

  48. COVID-19 has resulted in an increased demand for eHealth services globally. There is emerging evidence for the efficacy for group eHealth interventions that support population-based mental health and wellbeing...

    Authors: Cheryl L. Currie, Richard Larouche, M. Lauren Voss, Erin K. Higa, Rae Spiwak, David Scott and Treena Tallow

    Citation: Systematic Reviews 2020 9:217

    Content type: Protocol

    Published on:

  49. Biological changes underlying the sexual and reproductive maturation of school-age children are linked with various sexual and reproductive health and rights risks. SRHR risks are predictors of poor SRHR outco...

    Authors: Arone Wondwossen Fantaye, Amos Wung Buh, Dina Idriss-Wheeler, Karine Fournier and Sanni Yaya

    Citation: Systematic Reviews 2020 9:216

    Content type: Protocol

    Published on:

  50. Interventions to treat early prostate cancer (PCa) can leave men with debilitating sexual side effects. The cluster of side effects referred to as the neglected sexual side effects (NSSE) may remain permanent,...

    Authors: Pierre Röscher and Jacqueline M. van Wyk

    Citation: Systematic Reviews 2020 9:214

    Content type: Protocol

    Published on:

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